Bone Marrow Program
The best cure for Sickle Cell Disease, Acute lymphoblastic leukemia and other Blood disorders is bone marrow or stem cell transplant.
Bone marrow is a soft, fatty tissue inside the center of the bones where blood cells are made. A bone marrow or stem cell transplant is a procedure that takes healthy cells that form blood from one person—the donor and puts them into someone whose bone marrow is not working properly.
Bone marrow or stem cell transplants are very risky, and can have serious side effects, including death. For the transplant to work, the bone marrow must be a close match. Usually, the best donor is a relative or sibling sister or brother. Bone marrow or stem cell transplants are used only in cases of severe SCD for children who have minimal organ damage from the disease. Patients who do not have a suitable donor in their family, doctors may work with Center for health Services to find an adult volunteer donor match.
A doctor who is an expert in sickle cell disease can talk with you about your treatment options and explain the possible risks and benefits and the treatment you and your doctor decide. The time of diagnosis and transplant can affect transplant outcomes. To improve you or your child’s chances of a successful transplant, you and your doctor can plan ahead. A consultation with a transplant doctor can help determine whether a transplant is a good option for you.
For a patient’s body to accept these healthy cells, the patient needs a donor who is a close match. Seventy percent of patients do not have a donor in their family and depend on the donor registry to find an unrelated bone marrow donor or umbilical cord blood.
What is a Bone Marrow Transplant?
Bone marrow transplant is a life-saving treatment for people with sickle, cell blood cancers like leukemia and lymphoma, and other life-threatening diseases. First, the patients will undergo chemotherapy and sometimes radiation to destroy their diseased marrow. Then a donor’s healthy blood-forming cells are given directly into the patient’s bloodstream, where they can begin to function and multiply.
Study shows 70% of patients do not have a suitable donor in their family. If you do not have a donor in your family, your doctor can search for an unrelated donor or cord blood unit for you. Your doctor can work with donors registries around the world, the doctor can look for adult donors and cord blood units in the same search of the registry and choose the option that is best for you. There are million potential bone marrow and cord blood donors.
Center for Health Services Provide donor registry resources to help check if patients can find a match that can save life
Center for Health Services is a donor recruitment center for MARROW, UMBILICAL CORD and PLACENTA. These procedure are used to treat and help find cure for Sickle cell anemia, also for Leukemia, Lymphoma and other genetic diseases, these program is for people who from ages 18 – 44 years. A cheek swab or blood sample is tested to determine your tissue type and if a donor is a match. Center for health Services Partner with Be the Match- National Marrow Donor Program and Life Source to help save life. Join now.
Every year, thousands of adults and children need a marrow transplant, a procedure that may be their only chance for survival. Although some transplant patients have a genetically matched family member who can donate, about 70 percent do not. These patients’ lives depend on finding an unrelated individual with a compatible tissue type, often within their own ethnic group, who is willing to donate marrow.
Marrow transplantation has become the only real “cure” for many diseases.
The following is a list of some of the diseases most commonly treated by marrow transplants:
• Sickle Cell
• Acute lymphoblastic leukemia
• Acute myelogenous leukemia
• Chronic myelogenous leukemia
• Histiocytic disorders
• Hodgkin’s lymphoma
• Inherited erythrocyte abnormalities (e.g. Fanconi anemia, pure red cell aplasia)
• Inherited immune system disorders
• Myelodysplastic disorders
• Non-Hodgkin lymphoma
• Other leukemias
• Other malignancy
• Other non-malignant diseases
• Plasma cell disorder
• Severe aplastic anemia
Seventy-six percent of patients receiving Be The Match-facilitated transplants have some form of leukemia.
How to Get Involved
To Join Be The Match, You Must…
Be between the ages of 18 – 44 years old
Complete a brief health questionnaire to verify your eligibility to join the Registry
Sign a form consenting to have your tissue type listed on the Registry until your 61st birthday
Provide a blood sample or cheek swab which is tested to determine your tissue type
How does a person’s race or ethnicity affect matching?
Because tissue type is inherited, patients are most likely to match someone of their same race and ethnicity. While donors of all types may help save lives, there is a serious shortage of marrow/stem cell donors who represent ethnic minorities.
How are blood-forming cells collected?
Marrow donation is a surgical procedure performed in a hospital. While the donor receives anesthesia, doctors use special, hollow needles to withdraw liquid marrow from the donor’s pelvic bones. A donor’s marrow is completely replaced within four to six weeks.
Peripheral Blood Stem Cell (PBSC) donation takes place at an apheresis center. To increase the number of blood-forming cells in the bloodstream, donors receive daily injections of a drug called filgrastim for five days before the collection. The donor’s blood is then removed through a sterile needle in one arm and passed through a machine that separates out the cells used in transplantation; the remaining blood is then returned through the other arm.
Does donating hurt? What are the side effects?
Marrow donors can expect to feel some soreness in their lower back for a few days or longer. Donors also have reported feeling tired and having some difficulty walking. Most donors are back to their usual routine in a few days. Some may take two to three weeks before they feel completely recovered.
PBSC donors report varying symptoms, including headache, bone or muscle pain, nausea, insomnia and fatigue while receiving injections of filgrastim. These effects disappear shortly after collection. During the collection, donors may experience a tingling feeling or chills; these effects also go away shortly after donating.
When asked about their discomfort, most donors are quick to point out that it was worth it to help save a life and they would be willing to do it again.
How does a patient receive a transplant?
After a patient undergoes chemotherapy and/or radiation treatment to destroy their diseased marrow, the healthy donor cells are given directly into the patient’s bloodstream. The cells travel to the marrow, where they begin to function and multiply.